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HUGO Gene Nomenclature Committee
HGNC Approved SymbolHGNC Approved Name
SNORA80small nucleolar RNA, H/ACA box 80
snoid : SR0000299
Length : 135
Abstract : Homo sapiens ACA67 snoRNA. This H/ACA box RNA was characterized by bioinformatics, and its expression verified by Northern blot and primer extension in mouse (Schattner et al., 2006). As ACA42, ACA67 is predicted to guide the pseudouridylation of 18s rRNA U109 and U572. ACA67 is a primate-specific Type 1 snoRT (present in human, chimp, orangutan, rhesus, marmoset, not treeshrew), whose parental copy, ACA67B, resides in the ODC1 gene (Weber, 2006). A second primate-specific Type 1 ACA67B snoRTs resides in the JTV1 gene (chr7:6,023,034-6,023,168). A third one (extragenic, chr16:30,338,447-30,338,581) is embedded in a complex array of Alu elements. ACA42 might be an old ACA67B snoRT. A rodent-specific snoRT resides in the RPL6 gene, and a cow-specific one in the EIF2A gene.
GenBank accession number :
Host gene : C21orf108 mRNA
Click here to see the position on the UCSC Genome Browser
Target RNA : 18S rRNA U109 and 18S rRNA U572
sno/scaRNAs with same target 18S rRNA U109 : ACA42   ACA67B   
sno/scaRNAs with same target 18S rRNA U572 : ACA42   ACA67B   
References :
- Schattner, P., Barberan-Soler, S., and Lowe, T. M. (2006). A computational screen for mammalian pseudouridylation guide H/ACA RNAs. Rna 12, 15-25
- Weber MJ. (2006) Mammalian Small Nucleolar RNAs Are Mobile Genetic Elements. PLoS Genet. 2(12):e205
Sequence :
Phylogenic conservation: Alignment - Fasta file
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