ACA2a |
 |
HUGO Gene Nomenclature Committee | HGNC Approved Symbol | HGNC Approved Name | SNORA2A | small nucleolar RNA, H/ACA box 2A |
|
 | snoid :
SR0000077
|
 | Length :
135 |
 | Abstract :
Homo sapiens ACA2a snoRNA
This H/ACA box RNA was cloned by Kiss et al. (2004) from a HeLa cell extract immunoprecipitated with an anti-GAR1 antibody. As its close homologue ACA2b, it is predicted to guide pseudouridylation of U4263 and U4282 in 28S rRNA. The pseudouridylation of these residues was previously reported by Ofengand and Bakin (1997). The snoRNAs ACA2a, ACA2b and ACA34 share the same host gene (FLJ20436). |
 |
 | GenBank accession number :
AJ609426 |
 | Host gene : FLJ20436 (hypothetical protein,152aa ) |
 | Click here to see the position on the UCSC Genome Browser |
 | Target RNA : 28S rRNA U4263 and 28S rRNA U4282 |
 | sno/scaRNAs with same target 28S rRNA U4263 : ACA2b   |
 | sno/scaRNAs with same target 28S rRNA U4282 : ACA2b  ACA34   |
 | References : - Kiss, A. M., Jady, B. E., Bertrand, E., and Kiss, T. (2004). Human box H/ACA pseudouridylation guide RNA machinery. Mol. Cell .Biol. 24, 5797-5807 - Ofengand, J., and Bakin, A. (1997). Mapping to nucleotide resolution of pseudouridine residues in large subunit ribosomal RNAs from representative eukaryotes, prokaryotes, archaebacteria, mitochondria and chloroplasts. J Mol Biol 266, 246-268.
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 | Sequence :
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snoRNABase - http://www-snorna.biotoul.fr/ |