ACA57 |
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HUGO Gene Nomenclature Committee | HGNC Approved Symbol | HGNC Approved Name | SCARNA11 | small Cajal body-specific RNA 11 |
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 | snoid :
SR0000074
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 | Length :
137 |
 | Abstract :
Homo sapiens ACA57 scaRNA
This H/ACA box RNA was cloned by Kiss et al. (2004) from a HeLa cell extract immunoprecipitated with an anti-GAR1 antibody. It is predicted to guide the pseudouridylation of residue U43 of the U5 spliceosomal snRNA. The pseudouridylation of this residue was previously reported by Krol et al. (1981). As other modification guides of RNA polII-transcribed spliceosomal RNAs, ACA57 co-localizes with coilin in Cajal bodies after overexpression in HeLa cells. |
 |
 | GenBank accession number :
AJ609487 |
 | Host gene : CHD4 (Similar to chromodomain helicase DNA binding protein 4). |
 | Click here to see the position on the UCSC Genome Browser |
 | Target RNA : U5 snRNA U43 |
 | References : - Kiss, A. M., Jady, B. E., Bertrand, E., and Kiss, T. (2004). Human box H/ACA pseudouridylation guide RNA machinery. Mol. Cell .Biol. 24, 5797-5807 - Krol, A., Gallinaro, H., Lazar, E., Jacob, M., and Branlant, C. (1981). The nuclear 5S RNAs from chicken, rat and man. U5 RNAs are encoded by multiple genes. Nucleic Acids Res, 9, 769-787.
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 | Sequence :
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snoRNABase - http://www-snorna.biotoul.fr/ |
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