HBII-436 |
 |
HUGO Gene Nomenclature Committee | HGNC Approved Symbol | HGNC Approved Name | SNORD107 | small nucleolar RNA, C/D box 107 |
|
 | snoid :
SR0000132
|
 | Length :
75 |
 | Abstract :
Homo sapiens C/D box snoRNA HBII-436. This snoRNA was discovered by computer aided search of conserved sequences and structural motifs near the SNURF-SNRPN gene in the Prader-Willi locus (15q11-q13). It is expressed in brain, kidney, lung, and, to a lesser extent, heart, muscle and liver. It is not expressed in the brain of a Prader-Willi syndrome patient, but in the brain from an Angelman syndrome patient, showing its expression from the paternal allele only. HBII-436 ( as HBII-437, HBII-438A/B and the two clusters of HBII-52 and HBII-85 snoRNAs) is encoded in an intron of the large (460kb), paternally expressed, transcription unit (SNURF-SNRNP-UBE3A AS), that is antisense to the maternally expressed UBE3A gene. This snoRNA has no identified RNA target.
HBII-436 presents sequence similarities with SNORD119 (host gene SNRPB), which might be its ancestor. |
 | GenBank accession number :
AY055806 |
 | Host gene : SNURF-SNRNP-UBE3A AS |
 | Click here to see the position on the UCSC Genome Browser |
 | Target RNA : unknown |
 | References : - Runte, M., Huttenhofer, A., Gross, S., Kiefmann, M., Horsthemke, B., and Buiting, K. (2001). The IC-SNURF-SNRPN transcript serves as a host for multiple small nucleolar RNA species and as an antisense RNA for UBE3A. Hum Mol Genet, 10, 2687-2700.
|
 | Sequence :
|
snoRNABase - http://www-snorna.biotoul.fr/ |
|