|HUGO Gene Nomenclature Committee|
|HGNC Approved Symbol||HGNC Approved Name|
|SNORD127||small nucleolar RNA, C/D box 127|
Homo sapiens C/D box snoRNA SNORD127. This C/D box snoRNA was characterized by Yang et al. (2006) using the snoSeeker software. Its expression was experimentally verified by Northern blot. It is predicted to guide the 2’O-ribose methylation of 18S rRNA G1447. Methylation at that position was established by Maden and Salim(1974).
This snoRNA is incorrectly named SNORD118 in Yang et al. (2006) and in GenBank file AM413025, and should not be confused with U8 (HGCN approved symbol SNORD118).
|GenBank accession number :
|Host gene : PRPF39 (PRP39 pre-mRNA processing factor 39 homolog (S. cerevisiae))|
|Click here to see the position on the UCSC Genome Browser|
|Target RNA : 18S rRNA G1447|
- Yang,J.H., Zhang,X.C., Huang,Z.P., Zhou,H., Huang,M.B., Zhang,S.,Chen,Y.Q. and Qu,L.H. (2006)
snoSeeker: an advanced computational package for screening of guide and orphan snoRNA genes in the human genome. Nuc. Acids Res. 34:5112-5123
- Maden, B. E., and Salim, M. (1974). The methylated nucleotide sequences in HeLa cell ribosomal RNA and its precursors. J Mol Biol 88, 133-152.
|snoRNABase - http://www-snorna.biotoul.fr/|