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HUGO Gene Nomenclature Committee
HGNC Approved SymbolHGNC Approved Name
SNORD112small nucleolar RNA, C/D box 112
snoid : SR0000090
Length : 77
Abstract : Homo sapiens C/D box snoRNA 14q(0). This snoRNA was characterized by its conservation in human and ovine genomes in the region involved in the ovine mutation callypige. As the 9 copies of the snoRNA 14q(I) and the 31 copies of 14q(II), 14q(0) is encoded in an intron of the non-coding MEG8 RNA gene. Although near from the maternally expressed GTL2/MEG3 gene, the MEG8 gene is not submitted to genomic imprinting. In the human, 14q(0) is highly expressed in the brain and uterus, and to a lesser extent in the heart. This snoRNA is not predicted to guide to 2'O-methylation of a rRNA or snRNA.
GenBank accession number : NR_003080
Host gene : MEG8 non-coding RNA gene
Click here to see the position on the UCSC Genome Browser
Target RNA : unknown
References :
- Cavaille, J., Seitz, H., Paulsen, M., Ferguson-Smith, A. C., and Bachellerie, J. P. (2002). Identification of tandemly-repeated C/D snoRNA genes at the imprinted human 14q32 domain reminiscent of those at the Prader-Willi/Angelman syndrome region. Hum Mol Genet, 11, 1527-1538.
Sequence :
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