Homo sapiens ACA14a snoRNA
This H/ACA box RNA was cloned by Kiss et al. (2004) from a HeLa cell extract immunoprecipitated with an anti-GAR1 antibody. As its close paralogue ACA14b, it is predicted to guide the pseudouridylation of residue U966 of 18S rRNA. Maden and Wakeman (1988) could not determine whether U966, U968 or U969 was modified. The pseudouridylation of residue U966 was experimentally confirmed by primer extension mapping by Kiss et al. (2004).