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ACA17

HUGO Gene Nomenclature Committee
HGNC Approved Symbol	HGNC Approved Name
SNORA17	small nucleolar RNA, H/ACA box 17

snoid : SR0000366

Length : 133

Abstract : Homo sapiens ACA17 snoRNA This H/ACA box RNA was cloned by Kiss et al. (2004) from a HeLa cell extract immunoprecipitated with an anti-GAR1 antibody. It is predicted to guide the pseudouridylation of residues U4659, U4598 and U4937 of 28S rRNA (Kiss et al., 2004; Schattner et al., 2006). The pseudouridylation of these residues was previously reported by Ofengand and Bakin (1997). ACA17 and ACA43 share the same host gene

GenBank accession number : AJ609434

Host gene : Cluster of mRNAs/ESTs (Unigene Hs.549706, hypothetical protein MGC16037, significant homology with human collagen alpha 1).

Click here to see the position on the UCSC Genome Browser

Target RNA : 28S rRNA U4598 and 28S rRNA U4659 and 28S rRNA U4937

References :
- Kiss, A. M., Jady, B. E., Bertrand, E., and Kiss, T. (2004). Human box H/ACA pseudouridylation guide RNA machinery. Mol. Cell .Biol. 24, 5797-5807
- Ofengand, J., and Bakin, A. (1997). Mapping to nucleotide resolution of pseudouridine residues in large subunit ribosomal RNAs from representative eukaryotes, prokaryotes, archaebacteria, mitochondria and chloroplasts. J Mol Biol 266, 246-268.
- Schattner, P., Barberan-Soler, S., and Lowe, T. M. (2006). A computational screen for mammalian pseudouridylation guide H/ACA RNAs. Rna 12, 15-25

Sequence :

Phylogenic conservation: Alignment - Fasta file

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