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ACA19

HUGO Gene Nomenclature Committee
HGNC Approved Symbol	HGNC Approved Name
SNORA19	small nucleolar RNA, H/ACA box 19

snoid : SR0000043

Length : 128

Abstract : Homo sapiens ACA19 snoRNA This H/ACA box RNA was cloned by Kiss et al. (2004) from a HeLa cell extract immunoprecipitated with an anti-GAR1 antibody. It is predicted to guide the pseudouridylation of residues U3618 and U3709 of 28S rRNA. The pseudouridylation of these residues was previously reported by Ofengand and Bakin (1997). Schattner et al. (2006) predicted that ACA19 might also guide the pseudouridylation of 18S rRNA U863

GenBank accession number : AJ609435

Host gene : EIF3S10 (eukaryotic translation initiation factor 3, subunit 10 theta, 150/170kDa)

Click here to see the position on the UCSC Genome Browser

Target RNA : 28S rRNA U3618 and 28S rRNA U3709

References :
- Kiss, A. M., Jady, B. E., Bertrand, E., and Kiss, T. (2004). Human box H/ACA pseudouridylation guide RNA machinery. Mol. Cell .Biol. 24, 5797-5807
- Ofengand, J., and Bakin, A. (1997). Mapping to nucleotide resolution of pseudouridine residues in large subunit ribosomal RNAs from representative eukaryotes, prokaryotes, archaebacteria, mitochondria and chloroplasts. J Mol Biol 266, 246-268.
- Schattner, P., Barberan-Soler, S., and Lowe, T. M. (2006). A computational screen for mammalian pseudouridylation guide H/ACA RNAs. Rna 12, 15-25

Sequence :

Phylogenic conservation: Alignment - Fasta file

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