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ACA68

HUGO Gene Nomenclature Committee
HGNC Approved Symbol	HGNC Approved Name
SCARNA21	small Cajal body-specific RNA 21

snoid : SR0000231

Length : 138

Abstract : Homo sapiens ACA68 scaRNA. This H/ACA box RNA was characterized by bioinformatics, and its expression verified by Northern blot and primer extension in mouse (Schattner et al., 2006). It is predicted to guide the pseudouridylation of U12 snRNA U19. The pseudouridylation of this nucleotide was experimentally demonstrated by Massenet et al. (2002). As other modification guides of snRNAs transcribed by RNA polII, ACA68 is predicted to reside in Cajal bodies.

GenBank accession number :

Host gene : CHD3 (chromodomain helicase DNA binding protein 3)

Click here to see the position on the UCSC Genome Browser

Target RNA : U12 snRNA U19

References :
- Massenet, S., Mougin, A. and Branlant, C. (1998) Posttranscriptional modification in the U small nuclear RNAs, p.201-227. In H. Grosjean and R. Benne (ed.), Modification and editing of RNA. ASM Press, Washington D.C.
- Schattner, P., Barberan-Soler, S., and Lowe, T. M. (2006). A computational screen for mammalian pseudouridylation guide H/ACA RNAs. Rna 12, 15-25

Sequence :

Phylogenic conservation: Alignment - Fasta file

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