Abstract :
Homo sapiens ACA8 snoRNA
This H/ACA box RNA was cloned by Kiss et al. (2004) from a HeLa cell extract immunoprecipitated with an anti-GAR1 antibody. It is predicted to guide the pseudouridylation of residues U1056 and U1081 of 18S rRNA. The pseudouridylation of these residues was previously reported by Maden and Wakeman (1988). Schattner et al. (2006) predicted that ACA8 can also guide the pseudouridylation of 28S rRNA U3832 (as snoRNA E2). ACA1, ACA8, ACA18, ACA25, ACA32 and ACA40 and the C/D box snoRNAs mgh28S-2409 and mgh28S-2411 share the same host gene (MGC5306).
GenBank accession number :
Host gene : MGC5306 (hypothetical protein FLJ23363, 278aa).
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Target RNA : 18S rRNA U1056 and 18S rRNA U1081 and 28S rRNA U3832
