Homo sapiens HBI-36 snoRNA
This H/ACA box snoRNA was first cloned from a mouse adult brain cDNA library by Cavaillé et al. (2000), and found to be specifically expressed in the choroids plexus. Its human orthologue, HBI-36 was discovered by a BLASTN database search, and was found to be specifically expressed in the brain. Its gene resides in the second intron of the serotonin receptor 2c (5HT-2c) gene, which is predominantly expressed in choroids plexus epithelial cells. Interestingly, the human 5HT-2c mRNA was predicted to be 2'O-methylated by the C/D box snoRNP HBII-52 at a position also subjected to A:I editing. HBI-36 has no documented RNA target. The sequence of MBI-36 was deposited in GeneBank under accession: AF357423.
GenBank accession number :
Host gene : HTR2C (serotonin receptor 5HT-2C)
Click here to see the position on the UCSC Genome Browser