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HBI-36

HUGO Gene Nomenclature Committee
HGNC Approved Symbol	HGNC Approved Name
SNORA35	small nucleolar RNA, H/ACA box 35

snoid : SR0000370

Length : 127

Abstract : Homo sapiens HBI-36 snoRNA This H/ACA box snoRNA was first cloned from a mouse adult brain cDNA library by Cavaillé et al. (2000), and found to be specifically expressed in the choroids plexus. Its human orthologue, HBI-36 was discovered by a BLASTN database search, and was found to be specifically expressed in the brain. Its gene resides in the second intron of the serotonin receptor 2c (5HT-2c) gene, which is predominantly expressed in choroids plexus epithelial cells. Interestingly, the human 5HT-2c mRNA was predicted to be 2'O-methylated by the C/D box snoRNP HBII-52 at a position also subjected to A:I editing. HBI-36 has no documented RNA target. The sequence of MBI-36 was deposited in GeneBank under accession: AF357423.

GenBank accession number :

Host gene : HTR2C (serotonin receptor 5HT-2C)

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Target RNA : unknown

References :
- Cavaille, J., Buiting, K., Kiefmann, M., Lalande, M., Brannan, C. I., Horsthemke, B., Bachellerie, J. P., Brosius, J., and Huttenhofer, A. (2000). Identification of brain-specific and imprinted small nucleolar RNA genes exhibiting an unusual genomic organization. Proc Natl Acad Sci U S A, 97, 14311-14316.

Sequence :

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