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HUGO Gene Nomenclature Committee
HGNC Approved SymbolHGNC Approved Name
SNORD105Bsmall nucleolar RNA, C/D box 105B
snoid : SR0000477
Length : 79
Abstract : Homo sapiens U105B snoRNA. This C/D box snoRNA was characterized by Yang et al. (2006) using the snoSeeker software. Its expression was not experimentally demonstrated. Both U105 and U105B reside in the same host gene (PPAN), and are predicted to guide the 2O-ribose methylation of 18S rRNA U799. They probably result from an ancient intragenic duplication. Whereas the rRNA anti-sense sequence of SNORD105 is highly conserved from human to fishes, the anti-sense sequence of U105B is partially deleted in several species including rhesus monkey. In tetraodon, fugu, stickleback and medaka, the PPAN gene contains a third paralog, U105C, with a 2bp insertion between the rRNA anti-sense sequence and the D box, possibly shifting upstream by 2 bases the methylation target.
GenBank accession number : AM413024
Host gene : PPAN (peter pan homolog)
Click here to see the position on the UCSC Genome Browser
Target RNA : 18S rRNA U799
sno/scaRNAs with same target 18S rRNA U799 : U105   
References :
- Yang,J.H., Zhang,X.C., Huang,Z.P., Zhou,H., Huang,M.B., Zhang,S.,Chen,Y.Q. and Qu,L.H. (2006) snoSeeker: an advanced computational package for screening of guide and orphan snoRNA genes in the human genome. Nuc. Acids Res. 34:5112-5123
Sequence :
Phylogenic conservation: Alignment - Fasta file
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