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HUGO Gene Nomenclature Committee
HGNC Approved SymbolHGNC Approved Name
SNORD12Csmall nucleolar RNA, C/D box 12C
snoid : SR0000297
Length : 79
Abstract : Homo sapiens C/D box snoRNA U106. This snoRNA was first cloned from a rat cDNA library, and its human orthologue identified by database search (Vitali et al., 2003). Upstream of the D and D' boxes, it contains two conserved, 9-10 nt long, antisense elements matching two 18S rRNA segments. However, the two predicted targets (18S rRNA G1536 and U1602) do not appear to be methylated. U106, the highly related snoRNA SNORD12B (Yang et al., 2006) and HBII-99 (SNORD12) share the same host gene (C20orf199), and have probably the same target (28S rRNA G3878). Consequently, the HGNC approved symbol for U106 was changed from SNORD106 to SNORD12C.
GenBank accession number : AY349607
Host gene : C20orf199(hypothetical protein, 92aa)
Click here to see the position on the UCSC Genome Browser
Target RNA : unknown
References :
- Vitali, P., Royo, H., Seitz, H., Bachellerie, J. P., Huttenhofer, A., and Cavaille, J. (2003). Identification of 13 novel human modification guide RNAs. Nucleic Acids Res 31, 6543-6551.
- Yang,J.H., Zhang,X.C., Huang,Z.P., Zhou,H., Huang,M.B., Zhang,S.,Chen,Y.Q. and Qu,L.H. (2006) snoSeeker: an advanced computational package for screening of guide and orphan snoRNA genes in the human genome. Nuc. Acids Res. 34:5112-5123
Sequence :
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