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U23
HUGO Gene Nomenclature Committee
HGNC Approved SymbolHGNC Approved Name
SNORA75small nucleolar RNA, H/ACA box 75
snoid : SR0000280
Length : 138
Abstract : Homo sapiens U23 snoRNA. This H/ACA box RNA was cloned by L.-H. Qu, P. Ganot and J.-P. Bachellerie (unpubl.). Its role in guiding pseudouridylation of U93 of 18S rRNA was evidenced by Ganot et al. (1997a). The pseudouridylation of this residue was experimentally confirmed by primer extension mapping (Kiss et al., 2004). U23 and the C/D box snoRNAs U20 and U82 share the same host gene (nucleolin). Vertebrate sequences presented reside in the nucleolin gene (intron 12). In the zebrafish, a close copy, U23-2, resides in intron 10.
GenBank accession number : AJ007015
Host gene : NCL (nucleolin)
Click here to see the position on the UCSC Genome Browser
Target RNA : 18S rRNA U93
References :
- Kiss, A. M., Jady, B. E., Bertrand, E., and Kiss, T. (2004). Human box H/ACA pseudouridylation guide RNA machinery. Mol. Cell .Biol. 24, 5797-5807
- Ganot, P., Bortolin, M. L., and Kiss, T. (1997a). Site-specific pseudouridine formation in preribosomal RNA is guided by small nucleolar RNAs. Cell 89, 799-809.
Sequence :
Phylogenic conservation: Alignment - Fasta file
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Last modified: 07/09/2007