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HUGO Gene Nomenclature Committee
HGNC Approved SymbolHGNC Approved Name
SNORD24small nucleolar RNA, C/D box 24
snoid : SR0000361
Length : 75
Abstract : Homo sapiens C/D box snoRNA U24. This snoRNA was initially characterized by a bioinformatics search for C/D motives in a vertebrate intron database (Qu et al., 1995). It is predicted to guide the 2'O-ribose methylation of both 28S rRNA C2338 and C2352. It is however possible that, as in yeast, U24 might guide the methylation of adjacent bases G2351 and A2350 (Kiss-Laszlo et al., 1996), although the methylation of A2350 is predicted to be guided by U76. U24 shares the same host gene with the C/D box snoRNA U36A, U36B and U36C (RPL7A). A second copy of U24, U24A, is present in cow, opossum, zebrafish and xenopus RPL7A gene.
GenBank accession number : Z48764
Host gene : RPL7A (ribosomal protein L7a)
Click here to see the position on the UCSC Genome Browser
Target RNA : 28S rRNA C2338 and 28S rRNA C2352
References :
- Kiss-Laszlo, Z., Henry, Y., Bachellerie, J. P., Caizergues-Ferrer, M., and Kiss, T. (1996). Site-specific ribose methylation of preribosomal RNA: a novel function for small nucleolar RNAs. Cell, 85, 1077-1088.
- Qu, L. H., Henry, Y., Nicoloso, M., Michot, B., Azum, M. C., Renalier, M. H., Caizergues-Ferrer, M., and Bachellerie, J. P. (1995). U24, a novel intron-encoded small nucleolar RNA with two 12 nt long, phylogenetically conserved complementarities to 28S rRNA. Nucleic Acids Res, 23, 2669-2676.
Sequence :
Phylogenic conservation: Alignment - Fasta file
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