Result of your search at snoRNA-LBME-d

Result of your query

U25

HUGO Gene Nomenclature Committee
HGNC Approved Symbol	HGNC Approved Name
SNORD25	small nucleolar RNA, C/D box 25

snoid : SR0000061

Length : 67

Abstract : Homo sapiens C/D box snoRNA U25. This snoRNA was initially characterized as a conserved intronic sequence in the U22 host gene, UHG. Other introns of the same gene host the C/D box snoRNAs U26-U31 (Tycowski, Shu and Steitz, 1996). U25 was postulated to guide the 2'O-ribose methylation of 18S rRNA G1490 by Kiss-Laszlo et al. (1996). This was experimentally verifed in Xenopus oocytes by Tycowski et al. (1996).

GenBank accession number :

Host gene : U22 host gene (UHG)

Click here to see the position on the UCSC Genome Browser

Target RNA : 18S rRNA G1490

References :
- Kiss-Laszlo, Z., Henry, Y., Bachellerie, J. P., Caizergues-Ferrer, M., and Kiss, T. (1996). Site-specific ribose methylation of preribosomal RNA: a novel function for small nucleolar RNAs. Cell, 85, 1077-1088.
- Tycowski, K. T., Shu, M. D., and Steitz, J. A. (1996). A mammalian gene with introns instead of exons generating stable RNA products. Nature, 379, 464-466.
- Tycowski, K. T., Smith, C. M., Shu, M. D., and Steitz, J. A. (1996). A small nucleolar RNA requirement for site-specific ribose methylation of rRNA in Xenopus. Proc Natl Acad Sci U S A, 93, 14480-14485.

Sequence :

Printer-friendly version