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HUGO Gene Nomenclature Committee
HGNC Approved SymbolHGNC Approved Name
SNORD26small nucleolar RNA, C/D box 26
snoid : SR0000060
Length : 75
Abstract : Homo sapiens C/D box snoRNA U26. This snoRNA was initially characterized as a conserved intronic sequence in the U22 host gene, UGH. Other introns of the same gene host the C/D box snoRNAs U25-U31 (Tycowski, Shu and Steitz, 1996). U26 was postulated to guide the 2'O-ribose methylation of 28S rRNA A389 by Kiss-Laszlo et al. (1996), although this 2'O-methylated base was not mapped by Maden (1990).
GenBank accession number :
Host gene : U22 Host Gene (UHG)
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Target RNA : 28S rRNA A389
References :
- Kiss-Laszlo, Z., Henry, Y., Bachellerie, J. P., Caizergues-Ferrer, M., and Kiss, T. (1996). Site-specific ribose methylation of preribosomal RNA: a novel function for small nucleolar RNAs. Cell, 85, 1077-1088.
- Tycowski, K. T., Shu, M. D., and Steitz, J. A. (1996). A mammalian gene with introns instead of exons generating stable RNA products. Nature, 379, 464-466.
- Maden, B. E. (1990). The numerous modified nucleotides in eukaryotic ribosomal RNA. Prog Nucleic Acid Res Mol Biol, 39, 241-303.
Sequence :
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