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U27

HUGO Gene Nomenclature Committee
HGNC Approved Symbol	HGNC Approved Name
SNORD27	small nucleolar RNA, C/D box 27

snoid : SR0000059

Length : 72

Abstract : Homo sapiens C/D box snoRNA U27. This snoRNA was initially characterized as a conserved intronic sequence in the U22 host gene, UHG. Other introns of the same gene host the C/D box snoRNAs U25 to U31 (Tycowski, Shu and Steitz, 1996). U27 was postulated to guide the 2'O-ribose methylation of 18S rRNA A27 by Kiss-Laszlo et al. (1996).

GenBank accession number :

Host gene : U22 host gene (UHG)

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Target RNA : 18S rRNA A27

References :
- Kiss-Laszlo, Z., Henry, Y., Bachellerie, J. P., Caizergues-Ferrer, M., and Kiss, T. (1996). Site-specific ribose methylation of preribosomal RNA: a novel function for small nucleolar RNAs. Cell, 85, 1077-1088.
- Tycowski, K. T., Shu, M. D., and Steitz, J. A. (1996). A mammalian gene with introns instead of exons generating stable RNA products. Nature, 379, 464-466.

Sequence :

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