Abstract :
Homo sapiens U64 snoRNA.
This H/ACA box RNA was cloned from a HeLa cells by Ganot et al. (1997b). Its role in guiding pseudouridylation of U4975 in 28S rRNA was evidenced by Ganot et al. (1997a). The pseudouridylation of this residue was previously reported by Ofengand and Bakin (1997). U64 and ACA10 share the same host gene.
The NMR stucture of U64 3' loop was determined by Theimer et al. (2007) and compared to the CAB-containing loop of hTR and U85 scaRNAs.
