HUGO Gene Nomenclature Committee HGNC Approved Symbol HGNC Approved Name SNORA68 small nucleolar RNA, H/ACA box 68
Homo sapiens U68 snoRNA.
This H/ACA box RNA was cloned from a HeLa cells by Ganot et al. (1997b). Its role in guiding pseudouridylation of U4393 in 28S rRNA was evidenced by Ganot et al. (1997a). The pseudouridylation of this residue was previously reported by Ofengand and Bakin (1997).
GenBank accession number :
Host gene : RPL18A (ribosomal protein L18a)
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Target RNA : 28S rRNA U4393
References : - Ganot, P., Bortolin, M. L., and Kiss, T. (1997a). Site-specific pseudouridine formation in preribosomal RNA is guided by small nucleolar RNAs. Cell 89, 799-809. - Ofengand, J., and Bakin, A. (1997). Mapping to nucleotide resolution of pseudouridine residues in large subunit ribosomal RNAs from representative eukaryotes, prokaryotes, archaebacteria, mitochondria and chloroplasts. J Mol Biol 266, 246-268. - Ganot, P., Caizergues-Ferrer, M., and Kiss, T. (1997b). The family of box ACA small nucleolar RNAs is defined by an evolutionarily conserved secondary structure and ubiquitous sequence elements essential for RNA accumulation. Genes Dev 11, 941-956. Sequence :