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mgU6-47

HUGO Gene Nomenclature Committee
HGNC Approved Symbol	HGNC Approved Name
SNORD7	small nucleolar RNA, C/D box 7

snoid : SR0000245

Length : 97

Abstract : Homo sapiens C/D box snoRNA mgU6-47. This snoRNA was initially characterized in the mouse genome by a bioinformatics search of anti-sense elements followed by CTGA (Tykowski et al., 1998). Its human orthologue was described by Zhou et al. (2002), and named Z30. It is predicted to guide the 2'O-ribose methylation of U6 snRNA A47. Zhou et al. (2002) showed that, in the fission yeast, mgU6-47 is required for the methylation of U6 snRNA A47.

GenBank accession number : AJ007733

Host gene : Cluster of ESTs (UniGene Hs.531042)

Click here to see the position on the UCSC Genome Browser

Target RNA : U6 snRNA A47

References :
- Tycowski, K. T., You, Z. H., Graham, P. J., and Steitz, J. A. (1998). Modification of U6 spliceosomal RNA is guided by other small RNAs. Mol Cell, 2, 629-638.
- Zhou, H., Chen, Y. Q., Du, Y. P., and Qu, L. H. (2002). The Schizosaccharomyces pombe mgU6-47 gene is required for 2'-O-methylation of U6 snRNA at A41. Nucleic Acids Res, 30, 894-902.

Sequence :

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