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mgU6-77

HUGO Gene Nomenclature Committee
HGNC Approved Symbol	HGNC Approved Name
SNORD10	small nucleolar RNA, C/D box 10

snoid : SR0000229

Length : 148

Abstract : Homo sapiens C/D box snoRNA mgU6-77. This snoRNA is the human orthologue of the mouse snoRNA mgU6-77 characterized by a bioinformatics search of anti-sense elements followed by CTGA in the mouse genome (Tykowski et al., 1998). It is predicted to guide the 2'O-ribose methylation of both U6 snRNA C77 and 28S rRNA C3787. In Xenopus oocytes, mgU6-47 is required for the methylation of the corresponding nucleotides in U6 snRNA and 28S rRNA. mgU6-77 shares the same host gene with the H/ACA box snoRNAs U67 and ACA48 (EIF4A1).

GenBank accession number : NR_002604

Host gene : EIF4A1 (eukaryotic initiation factor 4A-I)

Click here to see the position on the UCSC Genome Browser

Target RNA : U6 snRNA C77 and 28S rRNA C3787

References :
- Tycowski, K. T., You, Z. H., Graham, P. J., and Steitz, J. A. (1998). Modification of U6 spliceosomal RNA is guided by other small RNAs. Mol Cell, 2, 629-638.

Sequence :

Phylogenic conservation: Alignment - Fasta file

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