ACA12 |
 |
HUGO Gene Nomenclature Committee | HGNC Approved Symbol | HGNC Approved Name | SCARNA23 | small Cajal body-specific RNA 23 |
|
 | snoid :
SR0000367
|
 | Length :
130 |
 | Abstract :
Homo sapiens ACA12 snoRNA
This H/ACA box RNA was cloned by Kiss et al. (2004) from a HeLa cell extract immunoprecipitated with an anti-GAR1 antibody. It is predicted to guide the pseudouridylation of residue U40 of the spliceosomal U6 snRNA. The pseudouridylation of this residue was previously reported by Epstein et al. (1980). In mouse and rat genomes, ACA12 sequences that reside in the expected intron of the PolA gene appear not functional. In these species, the pseudouridylation of U6snRNA U40 might be guided by HBI-100. |
 |
 | GenBank accession number :
AJ609482 |
 | Host gene : POLA (DNA polymerase alpha catalytic subunit ,EC 2.7.7.7). |
 | Click here to see the position on the UCSC Genome Browser |
 | Target RNA : U6 snRNA U40 |
 | sno/scaRNAs with same target U6 snRNA U40 : HBI-100   |
 | References : - Kiss, A. M., Jady, B. E., Bertrand, E., and Kiss, T. (2004). Human box H/ACA pseudouridylation guide RNA machinery. Mol. Cell .Biol. 24, 5797-5807 - Epstein, P., Reddy, R., Henning, D., and Busch, H. (1980). The nucleotide sequence of nuclear U6 (4.7 S) RNA. J Biol Chem, 255, 8901-8906.
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 | Sequence :
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snoRNABase - http://www-snorna.biotoul.fr/ |