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ACA24

HUGO Gene Nomenclature Committee
HGNC Approved Symbol	HGNC Approved Name
SNORA24	small nucleolar RNA, H/ACA box 24

snoid : SR0000319

Length : 131

Abstract : Homo sapiens ACA24 snoRNA This H/ACA box RNA was cloned by Kiss et al. (2004) from a HeLa cell extract immunoprecipitated with an anti-GAR1 antibody. It is predicted to guide the pseudouridylation of residue U863 and U609 of 18S rRNA. The pseudouridylation of U863 was previously reported by Maden and Wakeman (1988). The pseudouridylation of U609 was experimentally confirmed by primer extension mapping by Kiss et al. (2004).

GenBank accession number : AJ609460

Host gene : Cluster of mRNAs/ESTs (Unigene Hs.535762 ).

Click here to see the position on the UCSC Genome Browser

Target RNA : 18S rRNA U863 and 18S rRNA U609

References :
- Kiss, A. M., Jady, B. E., Bertrand, E., and Kiss, T. (2004). Human box H/ACA pseudouridylation guide RNA machinery. Mol. Cell .Biol. 24, 5797-5807
- Maden, E. H., and Wakeman, J. A. (1988). Pseudouridine distribution in mammalian 18 S ribosomal RNA. A major cluster in the central region of the molecule. Biochem J 249, 459-464.

Sequence :

Phylogenic conservation: Alignment - Fasta file

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