Homo sapiens ACA2a snoRNA
This H/ACA box RNA was cloned by Kiss et al. (2004) from a HeLa cell extract immunoprecipitated with an anti-GAR1 antibody. As its close homologue ACA2b, it is predicted to guide pseudouridylation of U4263 and U4282 in 28S rRNA. The pseudouridylation of these residues was previously reported by Ofengand and Bakin (1997). The snoRNAs ACA2a, ACA2b and ACA34 share the same host gene (FLJ20436).