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ACA2a

HUGO Gene Nomenclature Committee
HGNC Approved Symbol	HGNC Approved Name
SNORA2A	small nucleolar RNA, H/ACA box 2A

snoid : SR0000077

Length : 135

Abstract : Homo sapiens ACA2a snoRNA This H/ACA box RNA was cloned by Kiss et al. (2004) from a HeLa cell extract immunoprecipitated with an anti-GAR1 antibody. As its close homologue ACA2b, it is predicted to guide pseudouridylation of U4263 and U4282 in 28S rRNA. The pseudouridylation of these residues was previously reported by Ofengand and Bakin (1997). The snoRNAs ACA2a, ACA2b and ACA34 share the same host gene (FLJ20436).

GenBank accession number : AJ609426

Host gene : FLJ20436 (hypothetical protein,152aa )

Click here to see the position on the UCSC Genome Browser

Target RNA : 28S rRNA U4263 and 28S rRNA U4282

sno/scaRNAs with same target 28S rRNA U4263 : ACA2b

sno/scaRNAs with same target 28S rRNA U4282 : ACA2b ACA34

References :
- Kiss, A. M., Jady, B. E., Bertrand, E., and Kiss, T. (2004). Human box H/ACA pseudouridylation guide RNA machinery. Mol. Cell .Biol. 24, 5797-5807
- Ofengand, J., and Bakin, A. (1997). Mapping to nucleotide resolution of pseudouridine residues in large subunit ribosomal RNAs from representative eukaryotes, prokaryotes, archaebacteria, mitochondria and chloroplasts. J Mol Biol 266, 246-268.

Sequence :

Phylogenic conservation: Alignment - Fasta file

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