Abstract :
Homo sapiens ACA42 snoRNA
This H/ACA box RNA was cloned by Kiss et al. (2004) from a HeLa cell extract immunoprecipitated with an anti-GAR1 antibody. It is predicted to guide the pseudouridylation of residues U109 and U572 of 18S rRNA. Maden and Wakeman (1988) could not determine whether U571, U572 or U573, and U109 or U110 were modified. ACA42 and ACA26 share the same host gene.
ACA42 presents sequence similarity with, and might be an ancient snoRT of, ACA37B.