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ACA43

HUGO Gene Nomenclature Committee
HGNC Approved Symbol	HGNC Approved Name
SNORA43	small nucleolar RNA, H/ACA box 43

snoid : SR0000365

Length : 136

Abstract : Homo sapiens ACA43 snoRNA This H/ACA box RNA was cloned by Kiss et al. (2004) from a HeLa cell extract immunoprecipitated with an anti-GAR1 antibody. It is predicted to guide the pseudouridylation of residue U4938 of 28S rRNA. The pseudouridylation of residue 4937, but not 4938 was reported by Ofengand and Bakin (1997). ACA43 and ACA17 share the same host gene.

GenBank accession number : AJ609446

Host gene : Cluster of mRNAs/ESTs (Unigene Hs.549706, hypothetical protein MGC16037, significant homology with human collagen alpha 1).

Click here to see the position on the UCSC Genome Browser

Target RNA : 28S rRNA U4938

References :
- Kiss, A. M., Jady, B. E., Bertrand, E., and Kiss, T. (2004). Human box H/ACA pseudouridylation guide RNA machinery. Mol. Cell .Biol. 24, 5797-5807
- Ofengand, J., and Bakin, A. (1997). Mapping to nucleotide resolution of pseudouridine residues in large subunit ribosomal RNAs from representative eukaryotes, prokaryotes, archaebacteria, mitochondria and chloroplasts. J Mol Biol 266, 246-268.

Sequence :

Phylogenic conservation: Alignment - Fasta file

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