Homo sapiens ACA44 snoRNA
This H/ACA box RNA was cloned by Kiss et al. (2004) from a HeLa cell extract immunoprecipitated with an anti-GAR1 antibody. It is predicted to guide the pseudouridylation of residues U822 and U686 of 18S rRNA. Maden and Wakeman (1988) could not determine whether U822 or U823 was modified. The pseudouridylation of residue U686 was experimentally confirmed by primer extension mapping by Kiss et al. (2004). ACA16, ACA44, ACA61 and the C/D box snoRNA HBII-420 share the same host gene.
The mouse ortholog, MBI-64 was cloned by Huttenhofer et al. (2001).