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ACA5b

HUGO Gene Nomenclature Committee
HGNC Approved Symbol	HGNC Approved Name
SNORA5B	small nucleolar RNA, H/ACA box 5B

snoid : SR0000348

Length : 135

Abstract : Homo sapiens ACA5b snoRNA This H/ACA box RNA was cloned by Kiss et al. (2004) from a HeLa cell extract immunoprecipitated with an anti-GAR1 antibody. As its close paralogues ACA5 and ACA5c, this RNA is predicted to guide the pseudouridylation of residue U1238, and possibly U1625, of 18S rRNA. ACA5, ACA5b and ACA5c share the same host gene (TBRG4).

GenBank accession number :

Host gene : TBRG4 (transforming growth factor beta regulator 4, cell cycle progression 2 protein isoform 2, KIAA0948 protein)

Click here to see the position on the UCSC Genome Browser

Target RNA : 18S rRNA U1238

sno/scaRNAs with same target 18S rRNA U1238 : ACA5 ACA5c

References :
- Kiss, A. M., Jady, B. E., Bertrand, E., and Kiss, T. (2004). Human box H/ACA pseudouridylation guide RNA machinery. Mol. Cell .Biol. 24, 5797-5807

Sequence :

Phylogenic conservation: Alignment - Fasta file

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