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HUGO Gene Nomenclature Committee
HGNC Approved SymbolHGNC Approved Name
SNORD127small nucleolar RNA, C/D box 127
snoid : SR0000491
Length : 86
Abstract : Homo sapiens C/D box snoRNA SNORD127. This C/D box snoRNA was characterized by Yang et al. (2006) using the snoSeeker software. Its expression was experimentally verified by Northern blot. It is predicted to guide the 2O-ribose methylation of 18S rRNA G1447. Methylation at that position was established by Maden and Salim(1974). This snoRNA is incorrectly named SNORD118 in Yang et al. (2006) and in GenBank file AM413025, and should not be confused with U8 (HGCN approved symbol SNORD118).
GenBank accession number : AM413025
Host gene : PRPF39 (PRP39 pre-mRNA processing factor 39 homolog (S. cerevisiae))
Click here to see the position on the UCSC Genome Browser
Target RNA : 18S rRNA G1447
References :
- Yang,J.H., Zhang,X.C., Huang,Z.P., Zhou,H., Huang,M.B., Zhang,S.,Chen,Y.Q. and Qu,L.H. (2006) snoSeeker: an advanced computational package for screening of guide and orphan snoRNA genes in the human genome. Nuc. Acids Res. 34:5112-5123
- Maden, B. E., and Salim, M. (1974). The methylated nucleotide sequences in HeLa cell ribosomal RNA and its precursors. J Mol Biol 88, 133-152.
Sequence :
Phylogenic conservation: Alignment - Fasta file
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