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U103
HUGO Gene Nomenclature Committee
HGNC Approved SymbolHGNC Approved Name
SNORD103Asmall nucleolar RNA, C/D box 103A
snoid : SR0000009
Length : 91
Abstract : Homo sapiens C/D box snoRNA U103. This snoRNA was first cloned from a rat cDNA library, and its human orthologue identified by database search (Vitali et al., 2003). Two perfect copies, as well as the C/D box snoRNA HBII-251, reside in the same host gene (PUM1). U103 is predicted to guide the 2'O-ribose methylation of G601 of 18S rRNA (same target as HBII-251) . Note that the published sequence of U103 differs from the genomic sequence by 2 nts near its 3' end.
GenBank accession number : AY349604
Host gene : PUM1 (pumilio homolog 1 (Drosophila), RNA-binding protein that regulates translation and mRNA stability by binding the 3'UTR of mRNAs).
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Target RNA : 18S rRNA G601
sno/scaRNAs with same target 18S rRNA G601 : HBII-251   U103B   
References :
- Vitali, P., Royo, H., Seitz, H., Bachellerie, J. P., Huttenhofer, A., and Cavaille, J. (2003). Identification of 13 novel human modification guide RNAs. Nucleic Acids Res 31, 6543-6551.
Sequence :
Phylogenic conservation: Alignment - Fasta file
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