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U16

HUGO Gene Nomenclature Committee
HGNC Approved Symbol	HGNC Approved Name
SNORD16	small nucleolar RNA, C/D box 16

snoid : SR0000213

Length : 101

Abstract : Homo sapiens C/D box snoRNA U16. This snoRNA was originally characterized in an intron of the Xenopus laevis and human RPL1 genes by Fragapane et al. (1993). U16 was postulated to guide the 2'O-ribose methylation of 18S rRNA A484 by Kiss-Laszlo et al. (1996). U16 and three related copies of the C/D box snoRNA U18 share the same host gene (ribosomal protein L4, RPL4 or RPL1).

GenBank accession number :

Host gene : RPL4 (ribosomal protein L4)

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Target RNA : 18S rRNA A484

References :
- Kiss-Laszlo, Z., Henry, Y., Bachellerie, J. P., Caizergues-Ferrer, M., and Kiss, T. (1996). Site-specific ribose methylation of preribosomal RNA: a novel function for small nucleolar RNAs. Cell, 85, 1077-1088.
- Fragapane, P., Prislei, S., Michienzi, A., Caffarelli, E., and Bozzoni, I. (1993). A novel small nucleolar RNA (U16) is encoded inside a ribosomal protein intron and originates by processing of the pre-mRNA. Embo J, 12, 2921-2928.

Sequence :

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