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U18A

HUGO Gene Nomenclature Committee
HGNC Approved Symbol	HGNC Approved Name
SNORD18A	small nucleolar RNA, C/D box 18A

snoid : SR0000214

Length : 70

Abstract : Homo sapiens C/D box snoRNA U18A. This snoRNA was originally characterized in an intron of the Xenopus laevis and human RPL1 genes by Prislei et al. (1993). U18A was postulated to guide the 2'O-ribose methylation of 28S rRNA A1313 by Kiss-Laszlo et al. (1996). U18A, two related copies, U18B and U18C, and the C/D box snoRNA U16 share the same host gene (ribosomal protein L4, RPL4 or RPL1).

GenBank accession number :

Host gene : RPL4 (ribosomal protein L4)

Click here to see the position on the UCSC Genome Browser

Target RNA : 28S rRNA A1313

sno/scaRNAs with same target 28S rRNA A1313 : U18B U18C

References :
- Kiss-Laszlo, Z., Henry, Y., Bachellerie, J. P., Caizergues-Ferrer, M., and Kiss, T. (1996). Site-specific ribose methylation of preribosomal RNA: a novel function for small nucleolar RNAs. Cell, 85, 1077-1088.
- Prislei, S., Michienzi, A., Presutti, C., Fragapane, P., and Bozzoni, I. (1993). Two different snoRNAs are encoded in introns of amphibian and human L1 ribosomal protein genes. Nucleic Acids Res, 21, 5824-5830.

Sequence :

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