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U18B

HUGO Gene Nomenclature Committee
HGNC Approved Symbol	HGNC Approved Name
SNORD18B	small nucleolar RNA, C/D box 18B

snoid : SR0000212

Length : 70

Abstract : Homo sapiens C/D box snoRNA U18B. This snoRNA was originally characterized in an intron of the Xenopus laevis and human RPL1 genes by Prislei et al. (1993). U18B was postulated to guide the 2'O-ribose methylation of 28S rRNA A1313 by Kiss-Laszlo et al. (1996). U18B, two related copies, U18A and U18C, and the C/D box snoRNA U16 share the same host gene (ribosomal protein L4, RPL4 or RPL1).

GenBank accession number :

Host gene : RPL4 (ribosomal protein L4)

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Target RNA : 28S rRNA A1313

sno/scaRNAs with same target 28S rRNA A1313 : U18A U18C

References :
- Kiss-Laszlo, Z., Henry, Y., Bachellerie, J. P., Caizergues-Ferrer, M., and Kiss, T. (1996). Site-specific ribose methylation of preribosomal RNA: a novel function for small nucleolar RNAs. Cell, 85, 1077-1088.
- Prislei, S., Michienzi, A., Presutti, C., Fragapane, P., and Bozzoni, I. (1993). Two different snoRNAs are encoded in introns of amphibian and human L1 ribosomal protein genes. Nucleic Acids Res, 21, 5824-5830.

Sequence :

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