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U19-2
HUGO Gene Nomenclature Committee
HGNC Approved SymbolHGNC Approved Name
SNORA74Bsmall nucleolar RNA, H/ACA box 74B
snoid : SR0000328
Length : 204
Abstract : Homo sapiens U19-2 snoRNA. This H/ACA box RNA was cloned by Gu et al. (2005) from blood cells by an RT-PCR method that preferentially amplifies H/ACA box snoRNAs. Its expression was evidenced by Northern blot. As the closely related snoRNA U19, U19-2 is predicted to guide the pseudouridylation of 28S rRNA U3741 and U3743. The pseudouridylation of both bases has been evidenced by Ofengard and Bakin (1997). U19-2 is probably a primate-specific retroposon.
GenBank accession number : AM055743
Host gene : ATP6V0E (ATPase, H+ transporting, lysosomal, V0 subunit)
Click here to see the position on the UCSC Genome Browser
Target RNA : 28S rRNA U3741 and 28S rRNA U3743
sno/scaRNAs with same target 28S rRNA U3741 : U19   
sno/scaRNAs with same target 28S rRNA U3743 : U19   
References :
- Gu, A. D., Zhou, H., Yu, C. H., and Qu, L. H. (2005). A novel experimental approach for systematic identification of box H/ACA snoRNAs from eukaryotes. Nucleic Acids Res 33, e194.
- Ofengand, J., and Bakin, A. (1997). Mapping to nucleotide resolution of pseudouridine residues in large subunit ribosomal RNAs from representative eukaryotes, prokaryotes, archaebacteria, mitochondria and chloroplasts. J Mol Biol 266, 246-268.
Sequence :
Phylogenic conservation: Alignment - Fasta file
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