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HUGO Gene Nomenclature Committee
HGNC Approved SymbolHGNC Approved Name
SNORD22small nucleolar RNA, C/D box 22
snoid : SR0000054
Length : 126
Abstract : Homo sapiens C/D box snoRNA U22. This snoRNA was originally characterized among RNAs immunoprecipitated with an anti-(U3)RNP monoclonal antibody, and named RNA Y (Tyc and Steitz, 1989). Tycowski, Shu and Steitz (1994) later showed that U22 is required for the processing of 18S rRNA in Xenopus oocytes. U22 shares the same host gene (UHG) with several other C/D box snoRNAs (U25-U31). Exons of this gene are poorly conserved, and have little potential for protein coding (Tycowski, Shu and Steitz, 1996).
GenBank accession number :
Host gene : UHG (U22 Host Gene)
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Target RNA : unknown
References :
- Tycowski, K. T., Shu, M. D., and Steitz, J. A. (1996). A mammalian gene with introns instead of exons generating stable RNA products. Nature, 379, 464-466.
- Tyc, K., and Steitz, J. A. (1989). U3, U8 and U13 comprise a new class of mammalian snRNPs localized in the cell nucleolus. Embo J, 8, 3113-3119.
- Tycowski, K. T., Shu, M. D., and Steitz, J. A. (1994). Requirement for intron-encoded U22 small nucleolar RNA in 18S ribosomal RNA maturation. Science, 266, 1558-1561.
Sequence :
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