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U31

HUGO Gene Nomenclature Committee
HGNC Approved Symbol	HGNC Approved Name
SNORD31	small nucleolar RNA, C/D box 31

snoid : SR0000055

Length : 71

Abstract : Homo sapiens C/D box snoRNA U31. This snoRNA was initially characterized as a conserved intronic sequence in the U22 host gene, UGH. Other introns of the same gene host the C/D box snoRNAs U26-U30 (Tycowski, Shu and Steitz, 1996). U31 was postulated to guide the 2'O-ribose methylation of 28S rRNA G4166 by Kiss-Laszlo et al. (1996), although this methylated base was not mapped by Maden (1990).

GenBank accession number :

Host gene : U22 host gene (UHG)

Click here to see the position on the UCSC Genome Browser

Target RNA : 28S rRNA A4166

References :
- Kiss-Laszlo, Z., Henry, Y., Bachellerie, J. P., Caizergues-Ferrer, M., and Kiss, T. (1996). Site-specific ribose methylation of preribosomal RNA: a novel function for small nucleolar RNAs. Cell, 85, 1077-1088.
- Tycowski, K. T., Shu, M. D., and Steitz, J. A. (1996). A mammalian gene with introns instead of exons generating stable RNA products. Nature, 379, 464-466.
- Maden, B. E. (1990). The numerous modified nucleotides in eukaryotic ribosomal RNA. Prog Nucleic Acid Res Mol Biol, 39, 241-303.

Sequence :

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