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U33

HUGO Gene Nomenclature Committee
HGNC Approved Symbol	HGNC Approved Name
SNORD33	small nucleolar RNA, C/D box 33

snoid : SR0000265

Length : 83

Abstract : Homo sapiens C/D box snoRNA U33. This snoRNA is the human orthologue of mouse U33 snoRNA, initially characterized by a bioinformatics search for C/D motives in a vertebrate intron database (Nicoloso et al. 1996). It is predicted to guide the 2'O-ribose methylation of 18S rRNA U1326. Interestingly, this nucleotide is also pseudo-uridinated (Maden and Wakeman, 1988), but the corresponding guide remains unknown. U33 share the same host gene with the C/D box snoRNAs U32A, U34 and U35A (RPL13A).

GenBank accession number :

Host gene : RPL13A (ribosomal protein L13A)

Click here to see the position on the UCSC Genome Browser

Target RNA : 18S rRNA U1326

References :
- Maden, E. H., and Wakeman, J. A. (1988). Pseudouridine distribution in mammalian 18 S ribosomal RNA. A major cluster in the central region of the molecule. Biochem J 249, 459-464.
- Nicoloso, M., Qu, L. H., Michot, B., and Bachellerie, J. P. (1996). Intron-encoded, antisense small nucleolar RNAs: the characterization of nine novel species points to their direct role as guides for the 2'-O-ribose methylation of rRNAs. J Mol Biol, 260, 178-195.

Sequence :

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