Homo sapiens C/D box snoRNA U38B. This snoRNA was initially characterized by a bioinformatics search for C/D motives in a vertebrate intron database (Nicoloso et al. 1996). It is predicted to guide the 2'O-ribose methylation of 28S rRNA A1858. U38B shares the same host gene with a closely related copy, U38A, and the C/D box snoRNAs U40 and U55 (RPS8).