Homo sapiens C/D box snoRNA U48. This snoRNA was cloned by Kiss-Laszlo et al. (1996), and predicted to guide the 2'O-ribose methylation of 28S rRNA C2279, although the methylation site was not mapped by Maden (1990). U48 and the C/D box snoRNA U52 share the same host gene (C6orf48). Note that the genomic sequence differs from the published sequence (X96648) by 1nt.