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U67

HUGO Gene Nomenclature Committee
HGNC Approved Symbol	HGNC Approved Name
SNORA67	small nucleolar RNA, H/ACA box 67

snoid : SR0000230

Length : 137

Abstract : Homo sapiens U67 snoRNA. This H/ACA box RNA was cloned from HeLa cells by Ganot et al. (1997b). Its role in guiding pseudouridylation of U1445 in 18S rRNA was evidenced by Ganot et al. (1997a). The pseudouridylation of U1445 was experimentally confirmed by primer extension mapping by the same authors. U67, ACA48 and the C/D box snoRNA mgU6-77 share the same host gene (EIF4A1).

GenBank accession number : Y11161

Host gene : EIF4A1 (eukaryotic translation initiation factor 4A1)

Click here to see the position on the UCSC Genome Browser

Target RNA : 18S rRNA U1445

References :
- Ganot, P., Bortolin, M. L., and Kiss, T. (1997a). Site-specific pseudouridine formation in preribosomal RNA is guided by small nucleolar RNAs. Cell 89, 799-809.
- Ganot, P., Caizergues-Ferrer, M., and Kiss, T. (1997b). The family of box ACA small nucleolar RNAs is defined by an evolutionarily conserved secondary structure and ubiquitous sequence elements essential for RNA accumulation. Genes Dev 11, 941-956.

Sequence :

Phylogenic conservation: Alignment - Fasta file

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