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U92

HUGO Gene Nomenclature Committee
HGNC Approved Symbol	HGNC Approved Name
SCARNA8	small Cajal body-specific RNA 8

snoid : SR0000356

Length : 131

Abstract : Homo sapiens U92 scaRNA This H/ACA box RNA was cloned by Darzacq et al. (2002) from HeLa cells. U92 co-localizes with coilin in Cajal bodies, and is predicted to guide pseudouridylation of U34 and U44 in U2 snRNA. The modification of these two residues was experimentally established by Shibata et al. (1975).

GenBank accession number : AY077742

Host gene : FAM29A (hypothetical protein,955aa)

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Target RNA : U2 snRNA U34 and U2 snRNA U44

References :
- Darzacq, X., Jady, B. E., Verheggen, C., Kiss, A. M., Bertrand, E., and Kiss, T. (2002). Cajal body-specific small nuclear RNAs: a novel class of 2'-O-methylation and pseudouridylation guide RNAs. Embo J 21, 2746-2756.
- Shibata, H., Ro-Choi, T. S., Reddy, R., Choi, Y. C., Henning, D., and Busch, H. (1975). The primary nucleotide sequence of nuclear U-2 ribonucleic acid. The 5'-terminal portion of the molecule. J Biol Chem, 250, 3909-3920.

Sequence :

Phylogenic conservation: Alignment - Fasta file

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