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ACA25

HUGO Gene Nomenclature Committee
HGNC Approved Symbol	HGNC Approved Name
SNORA25	small nucleolar RNA, H/ACA box 25

snoid : SR0000065

Length : 134

Abstract : Homo sapiens ACA25 snoRNA This H/ACA box RNA was cloned by Kiss et al. (2004) from a HeLa cell extract immunoprecipitated with an anti-GAR1 antibody. It is predicted to guide the pseudouridylation of residues U801 and U814 of 18S rRNA. The pseudouridylation of these residues was previously reported by Maden and Wakeman (1988). ACA1, ACA8, ACA18, ACA25, ACA32 and ACA40 and the C/D box snoRNAs mgh28S-2409 and mgh28S-2411 share the same host gene (MGC5306).

GenBank accession number : AJ609461

Host gene : AK128061 (hypothetical protein FLJ46181, 126aa).

Click here to see the position on the UCSC Genome Browser

Target RNA : 18S rRNA U801 and 18S rRNA U814

sno/scaRNAs with same target 18S rRNA U814 : ACA63

References :
- Kiss, A. M., Jady, B. E., Bertrand, E., and Kiss, T. (2004). Human box H/ACA pseudouridylation guide RNA machinery. Mol. Cell .Biol. 24, 5797-5807
- Maden, E. H., and Wakeman, J. A. (1988). Pseudouridine distribution in mammalian 18 S ribosomal RNA. A major cluster in the central region of the molecule. Biochem J 249, 459-464.

Sequence :

Phylogenic conservation: Alignment - Fasta file

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