Homo sapiens U89 scaRNA
This RNA was cloned by Darzacq et al. (2002) from HeLa cells. It is composed of an H/ACA box domain and a C/D box domain, and is associated with both fibrillarin and Gar1p. U89 co-localizes with coilin in Cajal bodies, and is predicted to guide the pseudouridylation of residue U46 in U5 snRNA (as U85). The modification of this residue was experimentally established by Krol et al. (1981).